Chinese Agricultural Science Bulletin ›› 2012, Vol. 28 ›› Issue (32): 63-67.
Special Issue: 生物技术; 畜牧兽医
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Abstract:
To predict the spatial structure and B-cell epitopes of Mycoplasma suis ORF4 protein. The secondary structure, tertiary structure, hydrophilicity, flexible region, antigenic index and surface probability were predicted through the nucleotide sequence of AJ504999-ORF4 were analyzed by bioinformatics software and internet routine. The results showed that the potential B cell antigenic epitopes of Mycoplasma suis ORF4 protein were located at 28-34, 54-61aa, whose the secondary structure were without α-helix but rich in β-pleated sheet. Prediction of the spatial structure and B-cell epitopes of Mycoplasma suis ORF4 protein might laid the basis for studies of the design of epitopes vaccine.
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https://www.casb.org.cn/EN/Y2012/V28/I32/63