Abstract: In order to study the impact on yield and agronomic characters of a new hybrid maize cultivar‘Zhongdu 100’under different planting density and fertilizer rate, three planting density 42000, 48000, 60000 per hectare and three fertilizer 450, 600, 900 kg/hm² were set to study the change rules of yield and agronomic characters. The results showed that the different planting density, fertilizing amount and their interaction make the output to have the very significant differences. Moderately increasing the density and fertilizer can increase production, which was to reduce when overdose. The variation of agronomic characteristics was related to yield of maize. Eventually, the optimal planting density and fertilizer rate of‘Zhongdu 100’planted in a mountainous area were 48000 per hectare, and compound fertilizer 600 kg and carbamide 600 kg per hectare, while the yield was 7645.5 kg/hm². This experiment provided a scientific basis for high-yield cultivation of‘Zhongdu 100’in the mountain area of Sichuan Province.