Effects of Chinese Herbal Compounds as Immune Additives on Biochemical Indexes of Acipenser schrenckii

doi:10.11924/j.issn.1000-6850.casb18070085

Abstract

Abstract: [Objective]The objective of this paper is to study the effect of Chinese herbal compounds as immune additive on biochemical index in Amur sturgeon. [Method]The effects of Chinese herbal compound A (Herba artemisiae, Radix isatidis, etc.), Chinese herbal compound B (Notoginseng, Rhubarb, etc.) and Chinese herbal compound C (Liquorice, Honeysuckle etc.) on biochemical indicators of juvenile Amur sturgeons were studied by feeding fodders under the water temperature of 17 ℃. Each group has 200 Amur sturgeons and then the three traditional Chinese herbal compounds were added to the base feed by the quality of 2.0%, 1.0% and 2.5% in liquid form respectively. To feed the prepared feed daily to Amur sturgeons according to their body mass of 2.5 %, and the Amur sturgeons in the control group was given the same amount of basic feed for 35 d. After the drug administration, to collect the blood of vena caudalis from 15 Amur sturgeons in each group and the liver of Amur sturgeons were collected at the same time. The changes of the content of active substance and enzyme activity in serum and liver were determined. [Result]The results showed that the content of albumin (ALB) in liver of compound A was higher than which in the control group. And the content of ALB in serum of compound A was lower than which in the control group. The content of ALB in serum of compound B was higher than that in the control group. And the content of ALB in serum of compound C was lower than which in the control group but it was higher than which in the compound A. The ratio of albumin to globulin (ALB/GLB) in the liver of compound A was higher than that of the control group. The content of blood urea nitrogen (BUN) in serum of compound A was lower than that in the control group. There was no difference in the content of BUN in serum between compound B and compound C compared with the control group. The content of creatinine (CREA) in serum of compound A and compound C was lower than that in the control group. And the content of triglyceride (TG) in serum of compound B was higher than that in the control group. The activity of lactate dehydrogenase (LDH) in serum of compound B was significantly higher than that of the control group, while the activity of lactate dehydrogenase (LDH) in serum of compound A and compound C was significantly lower than that of the control group. [Conclusion]The study shows that compound B and compound C may cause certain damage to Amur sturgeon, and further study of appropriate dosages is needed. Compound A is added according to the weight of the original drug in the basic feed, which has a certain protective effect on the liver and kidney. And compound A is good to improve the immunity of Amur sturgeon.

CLC Number:

S942.5

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