In peanut producing areas of southern Henan, the absorption, distribution and utilization of nitrogen, phosphorus, potassium, calcium and sulfur among different peanut varieties were studied by field random block experiments under optimized fertilization conditions, aiming to provide technical support for rational application of fertilizers with the above elements in peanut production. Results showed that the contents of N, P and S in peanut kernel were high in ‘Zhuhua 1’ (5.150%), ‘Kainong 71’ (0.558%) and ‘Jihua1 3’ (0.277%), respectively; the contents of K and Ca in the stem and leaf were the highest, the content of K in‘Zhonghua16’ was 0.940% and the content of Ca in ‘Zhonghua 24’ was 1.637%, respectively. The accumulation rate of N, P and S in peanut kernel was the highest in ‘Yuhua 40’, which was 288.436, 25.505 and 15.263 kg/hm 2, respectively; the accumulation rate of K and Ca in the stem and leaf was highest in ‘Yuhua 37’ (80.760 kg/hm 2) and ‘Zhonghua 24’ (54.084 kg/hm 2), respectively. The demanding rate of N, P2O5, K2O, CaO and S for 100 kg peanut pod was 3.920-5.042, 0.905-1.293, 1.626-2.721, 0.777-1.150 and 0.270-0.343 kg, respectively. Under the experiment conditions, for producing 100 kg peanut pod, the demanding rate of nitrogen of ‘Yuhua 22’, phosphorus of ‘Zhonghua 24’, and potassium, calcium and sulfur of ‘Shanghua 5’ were the lowest, while the nitrogen demanding of ‘Zhuhua 1’, the phosphorus, potassium and sulfur demanding of ‘Kainong 71’, and the calcium demanding of ‘Zhonghua 24’ were the highest.