Abstract: To study the mechanism of fertilizer efficient utilization and nutrient uptake in wide uniform planting of wheat, the authors used the multi-point plot experiment and “3414” field fertilization design to analyze the fertilization (nitrogen, phosphorus, and potassium) effect and recommended dosage under different soil fertilities. The results showed that the nutrient utilization of nitrogen, phosphorus, and potassium significantly decreased with the increase of fertilization level, and first increased then decreased with the increase of the soil fertility level, the order was medium fertility > relatively low fertility > low fertility > relatively high fertility > high fertility. With the soil fertility increase, the recommended fertilizing amounts were N 107.9-171.8 kg/hm², P₂O₅ 88.2-112.1 kg/hm² and K₂O 35.4-56.2 kg/hm². The average values were N 138.3 kg/hm², P₂O₅ 101.4 kg/hm², and K₂O 45.4 kg/hm². The proportion of the three elements was N: P₂O₅: K₂O=1:0.73:0.33. Due to the content difference of nitrogen, phosphorus and potassium in different soil types, suitable fertilizing amount for wheat in wide uniform planting should be readjusted properly according to soil types.