Abstract: The aquaculture ecosystem was constructed under laboratory simulation conditions, and four cadmium exposure concentrations (0, 5, 50, and 100 μg?L^?1) were set to investigate the differences of enrichment and residue effects of cadmium in different edible parts (gonad, body meat and leg meat) of Eriocheir sinensis. The results showed that: 1 The residual value of cadmium in Eriocheir sinensis was gonad > body meat > leg meat, and the proportion of gonads was more than 85%. 2 The residual amount of cadmium in each edible part increased with exposure time, and it was positively correlated with the concentration of cadmium in the water environment. In the same edible part, the enrichment coefficient of low, medium and high concentration groups was negatively correlated with the cadmium concentration in the water environment; under the same concentration group, the enrichment coefficients of different edible parts were gonads > body meat > leg meat. 3 The residues of cadmium in Eriocheir sinensis may be have gender differences. The results systematically revealed the differences of cadmium enrichment in different edible parts of Eriocheir sinensis in water environment, and provide a theoretical basis for the distribution, enrichment and migration of cadmium in Eriocheir sinensis, and provide a scientific basis for the safe breeding and quality control.