Abstract:

The purpose of this study was to explore APS against Splenocytes apoptosis by lead cadmium toxicosis in chicken. Apoptosis rate of splenocytes and transcriptional level of Bcl-2 mRNA were detected by TUNEL method and RT-PCR in control, lead cadmium and APS-lead cadmium group. The results showed that: there were higher apoptotic rate and lower transcriptional level of Bcl-2 mRNA, compared with the controls; There were significant or very significant difference in control and experimental groups, and the data of APS-lead cadmium group was between control and lead cadmium groups. It suggested that APS could resisted splenocytes apoptosis by lead cadmium toxicosis significantly.