Abstract: With Lycium barbarum as test material, examined the effect of different irrigation on yield and quality of irrigation frequency, Lycium determine water production functions. Results showed that the wolfberry autumn fruit harvested in the water consumption of basic rendering and Autumn fruit growth stage for small, large vegetative growth, peak period of full productive age and characteristics of florescence; by fitting the yield and water consumption of Lycium barbarum and concluded that water production function was y=-1.2162x2+1461.07x-436857 (R2=0.7673), when water consumption to reach 600.68 mm, production reached 1965.47 kg/hm2, where irrigation frequency up to five times. Not only for the highest yield, so that relatively high water use efficiency, but also access to a better quality of Lycium barbarum, achieving high yield and efficient and uniform.