Abstract: This study tested the inhibitory activity of eight plant volatiles and extracts to Phytophthora cactorum and Fusarium solani, the casual agent of panax notoginseng root rot. The results revealed that the volatiles and extracts of Allium sativum, A. epa, A. tuberosum, A. fistulosum showed obvious inhibition activity against P. cactorum and F. solani and the inhibition activity of A. sativum is the strongest. The volatiles of Zingiber officinale, Houttuynia cordata, Coriandrum sativum and Mentha haplocalyx had little inhibiton activity on P. cactorum and F. solani, sometimes accelerated colony growth when treated with low concentration. However, the extracts of Z. officinale, the root and leaf of C. sativum showed obvious inhibitory activity to P. cactorum and F. solani. This data would provide scientific basis for using the rotation of these crops rotation to control Panax notoginseng root rot.