Nano-selenium Prepared by Biological Method: Research Progress and Application Prospect

doi:10.11924/j.issn.1000-6850.casb2021-0378

Abstract

Abstract:

Selenium is one of the trace elements required by human body, and it is very important for the survival and development of human beings. As a new type of bio-nanotechnology, the method of researching and preparing nano-selenium has attracted more and more attention and has broad application prospects. This article summarizes three methods of preparing nano-selenium, which are physical method, chemical method and biological method. It also introduces the synthesis of nano-selenium by biological method. This synthesis method has mild reaction conditions and fast reaction, and is pollution-free and sustainable, which is the best synthesis method among the three. This article also summarizes the common methods for characterizing nano-selenium in the past five years at home and abroad, such as transmission electron microscopy, Fourier infrared spectroscopy, X-ray diffraction and ultraviolet-visible absorption spectroscopy, and discusses the application direction of the selenium industry such as plant selenium supplementation, animal selenium supplementation and drug development, aiming to provide new ideas for the preparation of nano-selenium, and to explore the application prospects of nano-selenium.

Key words: nano-selenium, biological method, plant extracts, microorganisms, animal selenium supplementation, plant selenium supplementation, drug development

CLC Number:

YIN Tingting, LI Zhihui, SU Jiahe, WU Shidi, XU Hongyan, HE Shuai, LIU Pei, LI Xiangqian. Nano-selenium Prepared by Biological Method: Research Progress and Application Prospect[J]. Chinese Agricultural Science Bulletin, 2022, 38(8): 33-41.

Figures/Tables 3

References 92

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项目	无机硒	有机硒	纳米硒
吸收利用率	低	中	高
急性毒性LD₅₀	15 mg/kg	30~40 mg/kg	113 mg/kg
生物活性	低	中	高

项目	无机硒	有机硒	纳米硒
吸收利用率	低	中	高
急性毒性LD₅₀	15 mg/kg	30~40 mg/kg	113 mg/kg
生物活性	低	中	高

微生物种类	细分	前体材料	尺寸	参考文献
细菌	Bacillus mycoides SeITE01	亚硒酸盐	(160.6±52.24) nm	[29]
	大肠杆菌MG1655	亚硒酸钠	100~250 nm	[30]
	生防菌枯草芽孢杆菌	亚硒酸钠	50~250 nm	[31]
	嗜酸乳杆菌LA5	亚硒酸钠	80~150 nm	[32]
	Bacillus cereus CC-1	亚硒酸钠	100~200 nm	[33]
	贪铜杆菌	亚硒酸钠	196 nm	[34]
	Proteus mirabilis YC801	亚硒酸钠	(178.3±11.5) nm	[35]
	淀粉芽孢杆菌	亚硒酸钠	300 nm	[36]
	Pseudomonas aeruginosa	亚硒酸钠	140 nm	[37]
	Pantoea agglomerans	亚硒酸钠	30~300 nm	[38]
	Agrobacterium sp.	亚硒酸钠	140~200 nm	[39]
	Bacillus sp. MSh-1	亚硒酸钠	80~220 nm	[40]
	Acinetobacter sp. sW30	亚硒酸钠	100 nm	[41]
	植物乳杆菌	亚硒酸钠	(45.17±11.9) nm	[42]
真菌	Saccharomyces cerevisiae	亚硒酸钠	30~100 nm	[43]
	Aspergillus terreus	亚硒酸	47 nm	[44]
	酵母	亚硒酸钠	30~40 nm	[45]
	Mariannaea sp.	亚硒酸钠	45~211 nm	[18]
放线菌	Streptomyces bikiniensis strain	亚硒酸钠	17 nm	[46]
	Streptomyces microflavus strain FSHJ31	亚硒酸钠	28~123 nm	[47]
	filamentous bacterium Streptomyces sp. ES2	亚硒酸钠	50~500 nm	[48]
原生动物	Tetrahymena thermophila SB210	亚硒酸	50~500 nm	[49]

微生物种类	细分	前体材料	尺寸	参考文献
细菌	Bacillus mycoides SeITE01	亚硒酸盐	(160.6±52.24) nm	[29]
	大肠杆菌MG1655	亚硒酸钠	100~250 nm	[30]
	生防菌枯草芽孢杆菌	亚硒酸钠	50~250 nm	[31]
	嗜酸乳杆菌LA5	亚硒酸钠	80~150 nm	[32]
	Bacillus cereus CC-1	亚硒酸钠	100~200 nm	[33]
	贪铜杆菌	亚硒酸钠	196 nm	[34]
	Proteus mirabilis YC801	亚硒酸钠	(178.3±11.5) nm	[35]
	淀粉芽孢杆菌	亚硒酸钠	300 nm	[36]
	Pseudomonas aeruginosa	亚硒酸钠	140 nm	[37]
	Pantoea agglomerans	亚硒酸钠	30~300 nm	[38]
	Agrobacterium sp.	亚硒酸钠	140~200 nm	[39]
	Bacillus sp. MSh-1	亚硒酸钠	80~220 nm	[40]
	Acinetobacter sp. sW30	亚硒酸钠	100 nm	[41]
	植物乳杆菌	亚硒酸钠	(45.17±11.9) nm	[42]
真菌	Saccharomyces cerevisiae	亚硒酸钠	30~100 nm	[43]
	Aspergillus terreus	亚硒酸	47 nm	[44]
	酵母	亚硒酸钠	30~40 nm	[45]
	Mariannaea sp.	亚硒酸钠	45~211 nm	[18]
放线菌	Streptomyces bikiniensis strain	亚硒酸钠	17 nm	[46]
	Streptomyces microflavus strain FSHJ31	亚硒酸钠	28~123 nm	[47]
	filamentous bacterium Streptomyces sp. ES2	亚硒酸钠	50~500 nm	[48]
原生动物	Tetrahymena thermophila SB210	亚硒酸	50~500 nm	[49]

来源	前体材料	还原剂	尺寸	参考文献
Tarragon extract	亚硒酸钠	植物提取物	20~50 nm	[50]
Neem	硒	植物提取物	-	[51]
茶叶	亚硒酸钠	茶多糖	75 nm	[52]
昆布多糖	亚硒酸钠	抗坏血酸	60 nm	[53]
刺槐豆多糖	亚硒酸钠	抗坏血酸	95~100 nm	[54]
壳聚糖	亚硒酸钠	抗坏血酸	50 nm	[55]
Lemon(Citrus) plant	亚硒酸钠	植物提取物	60~80 nm	[56]
Emblica officinalis	亚硒酸钠	果实提取物	15~40 nm	[57]
Fenugreek	亚硒酸	种子提取物	50~150 nm	[58]
柠檬	亚硒酸	柠檬酸提取液	164.2~295.3 nm	[59]
Psidium guajava	亚硒酸钠	树叶提取物	8~20 nm	[60]
Diospyros montana	亚硒酸	树叶提取物	4~16 nm	[61]
Vitis vinifera	亚硒酸	水果提取物	3~18 nm	[62]
Theobroma cacao L. Bean Shell Extract	亚硒酸	果实提取物	50~500 nm	[63]
Green tea	亚硒酸钠	植物提取物	334.7 nm	[64]
紫菀叶提取物	亚硒酸	植物提取物	169 nm	[65]
Hawthorn fruit extract	亚硒酸钠	植物提取物	113 nm	[66]