Abstract:

Long-term addition of antibiotics in feed can cause the problems such as drug residues and bacterial resistance, leading to a decline in the quality of livestock and poultry products, threats to human health, and damage to the ecological environment. In 2020, Announcement No. 194 of the Ministry of Agriculture and Rural Affairs officially implemented, and the use of growth promoting antibiotic additives in feed was completely prohibited, marking the arrival of the era of "anti antibiotic" in the livestock and poultry industry. Non antibiotic breeding has become a major trend in the development of the livestock and poultry industry. Antibiotic substitutes can improve the growth performance of animals, improve intestinal health, and regulate the host immune system. They have the advantages of safety, efficiency, low residue, and low pollution, and have great prospects in the application of feed additives. Therefore, this article reviews the research progress in the application and action mechanism of green additives such as antibiotic substitutes, microecological agents, organic acids, plant extracts, Chinese herbal medicines, antimicrobial peptides, etc., in order to provide reference for healthy livestock breeding and promote the green and healthy development of livestock and poultry breeding in China.

Key words: livestock and poultry, antibiotic substitutes, green livestock farming, healthy farming, action mechanism, antibiotic alternatives, microecological agents, plant extracts, chinese herbal medicine, organic acid, antimicrobial peptides, livestock health