Abstract: T78 you 2155 was an early hybrid rice combination which is bred by Sanming Institute of Agricultural Science. It had been registered and released by the Crop Variety Appraisal Committee of Fujian, Guanxi and Guandong province. A comprehensive culture techniques for fine quality early rice-T78 you 2155 was studied by the method of optimization design. Three influential elements for the culture techniques were planting density (x1), quantities of nitrogen (x2) and leaf age in transplanting (x3). The regression models of three elements with yield were established. The results showed that the yield was influenced by three elements. After simulation screening and optimal selection by computer, the comprehensive culture techniques of high yield were 4.0~5.2 leaves for transplanting, as 165000~310000 hills per hm2, and 155~212kg N per hm2.