Research Progress on SIX Effectors of Fusarium oxysporum

doi:10.11924/j.issn.1000-6850.casb2024-0119

Abstract

Abstract:

Fusarium oxysporum (Fo) is a soil-borne fungal disease that causes crop wilting, which is a serious constraint to the sustainable development of agriculture. Effectors are key factors in pathogen-plant interactions, and their mechanism of action can be analyzed to provide effective strategies for controlling plant diseases. When Fo infects crops, it secretes a protein in the xylem of vascular bundles, which is called Secreted In Xylem effector protein (SIX). In order to study the role of SIX effectors between Fo and plants, the structural characteristics of SIX on the Fo genome were analyzed. The functional attributes of SIX in identifying different formae speciales and physiological races of Fo, influencing the pathogenicity of Fo, and affecting the immune response of plants were summarized. It was pointed out that SIX had toxic effects on plants and could interact with plants in an incompatible manner to influence the invasion of pathogens. The results of this study reveal the effects of SIX on plants in different aspects and provide theoretical support for the study of the molecular mechanism of plant disease resistance and the selection and breeding of disease-resistant varieties.

Key words: Fusarium oxysporum, pathogenicity, immune response, wilting disease, effector proteins, SIX effectors, structural characteristics, formae speciales and physiological races, avirulence genes

CHEN Yiwen, PENG Cunzhi, XU Bingqiang. Research Progress on SIX Effectors of Fusarium oxysporum[J]. Chinese Agricultural Science Bulletin, 2024, 40(36): 132-139.

Figures/Tables 3

References 67

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宿主	效应因子		区分功能		参考文献
番茄	SIX1、SIX2、SIX3、SIX5		Fol		[26]
	SIX4		Fol生理小种Ⅰ		[26]
	SIX3点突变		Fol生理小种Ⅱ、Ⅲ		[26]
棉花	SIX6		澳大利亚Fov		[27]
油棕	EF-1α、SIX8、SIX9、SIX11		FOE		[28]
香蕉	SIX6		Foc生理小种Ⅰ		[29]
	SIX8a		Foc生理小种Ⅳ		[35]
	SIX1		Foc热带小种Ⅳ		[29]
	SIX1a		Foc热带小种Ⅳ		[35]
	SIX1b、SIX1c、SIX2、SIX8a		Foc热带小种Ⅳ		[30]
	SIX7a		Foc亚热带小种Ⅳ		[35]
	SIX8		Foc亚热带小种Ⅳ		[29]
相思树	SIX1、SIX6		Fo koae		[31]
菠菜	SIX4、SIX8、SIX14（SIX8、SIX9）		F. oxysporum f. sp. Spinaciae		[32]
豌豆	SIX1、SIX6、SIX7、SIX9、SIX10、SIX11、SIX12、SIX14		FOP生理小种Ⅰ		[33]
豌豆	SIX1、SIX6、SIX9、SIX13、SIX14（SIX1、SIX6、SIX13）		FOP生理小种Ⅱ		[33]
西番莲		EF-1α、β -微管蛋白、SIX6、SIX9		F. oxysporum f. sp. passiflorae	[34]
油菜、紫罗兰		SIX9、SIX14		F. oxysporum f. sp. rapae、F. oxysporum f. sp. matthiolae	[36]
扁豆		SIX11		F. oxysporum f. sp. lentis	[37]

宿主	效应因子		区分功能		参考文献
番茄	SIX1、SIX2、SIX3、SIX5		Fol		[26]
	SIX4		Fol生理小种Ⅰ		[26]
	SIX3点突变		Fol生理小种Ⅱ、Ⅲ		[26]
棉花	SIX6		澳大利亚Fov		[27]
油棕	EF-1α、SIX8、SIX9、SIX11		FOE		[28]
香蕉	SIX6		Foc生理小种Ⅰ		[29]
	SIX8a		Foc生理小种Ⅳ		[35]
	SIX1		Foc热带小种Ⅳ		[29]
	SIX1a		Foc热带小种Ⅳ		[35]
	SIX1b、SIX1c、SIX2、SIX8a		Foc热带小种Ⅳ		[30]
	SIX7a		Foc亚热带小种Ⅳ		[35]
	SIX8		Foc亚热带小种Ⅳ		[29]
相思树	SIX1、SIX6		Fo koae		[31]
菠菜	SIX4、SIX8、SIX14（SIX8、SIX9）		F. oxysporum f. sp. Spinaciae		[32]
豌豆	SIX1、SIX6、SIX7、SIX9、SIX10、SIX11、SIX12、SIX14		FOP生理小种Ⅰ		[33]
豌豆	SIX1、SIX6、SIX9、SIX13、SIX14（SIX1、SIX6、SIX13）		FOP生理小种Ⅱ		[33]
西番莲		EF-1α、β -微管蛋白、SIX6、SIX9		F. oxysporum f. sp. passiflorae	[34]
油菜、紫罗兰		SIX9、SIX14		F. oxysporum f. sp. rapae、F. oxysporum f. sp. matthiolae	[36]
扁豆		SIX11		F. oxysporum f. sp. lentis	[37]

宿主	专化型	效应因子	致病因子	参考文献
香蕉	Foc热带生理小种Ⅳ	SIX1a	P	[38]
	Foc热带生理小种Ⅳ	SIX2、SIX6	P	[41]
	Foc热带生理小种Ⅳ	SIX8	P	[45]
番茄	Fol	SIX1、SIX3、SIX5、SIX6	P	[39]
棉花	Fov	SIX6	P	[42]
白菜	F. oxysporum f. sp. Conglutinans	SIX4	P	[44]

宿主	专化型	效应因子	致病因子	参考文献
香蕉	Foc热带生理小种Ⅳ	SIX1a	P	[38]
	Foc热带生理小种Ⅳ	SIX2、SIX6	P	[41]
	Foc热带生理小种Ⅳ	SIX8	P	[45]
番茄	Fol	SIX1、SIX3、SIX5、SIX6	P	[39]
棉花	Fov	SIX6	P	[42]
白菜	F. oxysporum f. sp. Conglutinans	SIX4	P	[44]

宿主	效应因子	靶标	无毒因子	参考文献
番茄	SIX1	I-3	P	[6]
番茄	SIX3	I-2	P	[59]
番茄	SIX4	I-1	P	[60]
草莓	SIX6	FW1	P	[64]
番茄	Avr2/SIX5	I-2	P	[65]